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BRE antibody

BRE Reactivity: Human, Mouse, Rat WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2423008
  • Target See all BRE Antibodies
    BRE (Brain and Reproductive Organ-Expressed (TNFRSF1A Modulator) (BRE))
    Reactivity
    • 27
    • 24
    • 22
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 40
    • 2
    Rabbit
    Clonality
    • 42
    Polyclonal
    Conjugate
    • 18
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This BRE antibody is un-conjugated
    Application
    • 31
    • 13
    • 13
    • 12
    • 10
    • 8
    • 7
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Purification
    Affinity purification
    Immunogen
    Recombinant protein of human BRE
    Isotype
    IgG
    Top Product
    Discover our top product BRE Primary Antibody
  • Application Notes
    WB 1:500-1:2000, IHC 1:50-1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.5 mg/mL
    Buffer
    PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
    Preservative
    Sodium azide
    Handling Advice
    Avoid freeze / thaw cycles.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    BRE (Brain and Reproductive Organ-Expressed (TNFRSF1A Modulator) (BRE))
    Alternative Name
    BABAM2 (BRE Products)
    Synonyms
    brcc4 antibody, brcc45 antibody, BRE antibody, LOC100231620 antibody, BRCC4 antibody, BRCC45 antibody, 6030405P19Rik antibody, AI429776 antibody, B830038C02Rik antibody, im:7141046 antibody, zgc:110368 antibody, BRISC and BRCA1 A complex member 2 antibody, brain and reproductive organ-expressed (TNFRSF1A modulator) antibody, BRISC and BRCA1 A complex member 2 L homeolog antibody, babam2 antibody, BABAM2 antibody, Babam2 antibody, BRE antibody, babam2.L antibody
    Background
    Brain and reproductive organ-expressed protein (BRE) is a 415 amino acid protein which binds to the intracellular juxtamembrane domain of the death receptor, tumor necrosis factor receptor 1 (TNF-R1). BRE also binds to the death receptor, FAS. BRE downregulates TNFa-induced activation of NFkB and may play a role in homeostasis or cellular differentiation in cells of epithelial, neural and germ line origins. It inhibits components of the death-inducing signaling complexes that are necessary for activation of the mitochondria, thereby mediating apoptosis. BRE is strongly expressed in the adrenal cortex, medulla, testis and pancreas, and is weakly expressed in the thymus, thyroid, stomach and small intestine.
    Molecular Weight
    Calculated MW: 44 kDa
    Pathways
    Positive Regulation of Response to DNA Damage Stimulus
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