PVRL4 antibody

Catalog No. ABIN2423877

Product Details anti-PVRL4 Antibody

Target: PVRL4 (Poliovirus Receptor-Related 4 (PVRL4))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PVRL4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Purification: Affinity purification

Immunogen: Recombinant protein of human PVRL4

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:100-1:300

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.9 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Preservative: Sodium azide

Handling Advice: Avoid freeze / thaw cycles.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PVRL4

Target: PVRL4 (Poliovirus Receptor-Related 4 (PVRL4))

Alternative Name: NECTIN4 (PVRL4 Products)

Synonyms: PVRL4 antibody, si:ch211-155e24.1 antibody, 1200017F15Rik antibody, Prr4 antibody, RGD1559826 antibody, EDSS1 antibody, LNIR antibody, PRR4 antibody, nectin-4 antibody, nectin cell adhesion molecule 4 antibody, NECTIN4 antibody, nectin4 antibody, Nectin4 antibody

Background: This gene encodes a member of the nectin family. The encoded protein contains two immunoglobulin-like (Ig-like) C2-type domains and one Ig-like V-type domain. It is involved in cell adhesion through trans-homophilic and -heterophilic interactions. It is a single-pass type I membrane protein. The soluble form is produced by proteolytic cleavage at the cell surface by the metalloproteinase ADAM17/TACE. The secreted form is found in both breast tumor cell lines and breast tumor patients. Mutations in this gene are the cause of ectodermal dysplasia-syndactyly syndrome type 1, an autosomal recessive disorder. Alternatively spliced transcript variants have been found but the full-length nature of the variant has not been determined.

Molecular Weight: Calculated MW: 55 kDa

Pathways: Cell-Cell Junction Organization