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Nicastrin antibody

NCSTN Reactivity: Human, Mouse, Rat WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2423883
  • Target See all Nicastrin (NCSTN) Antibodies
    Nicastrin (NCSTN)
    Reactivity
    • 38
    • 33
    • 22
    • 6
    • 6
    • 5
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 52
    • 2
    Rabbit
    Clonality
    • 44
    • 10
    Polyclonal
    Conjugate
    • 21
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Nicastrin antibody is un-conjugated
    Application
    • 40
    • 13
    • 13
    • 9
    • 7
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Purification
    Affinity purification
    Immunogen
    Recombinant protein of human NCSTN
    Isotype
    IgG
    Top Product
    Discover our top product NCSTN Primary Antibody
  • Application Notes
    WB 1:500-1:2000, IHC 1:50-1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.4 mg/mL
    Buffer
    PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
    Preservative
    Sodium azide
    Handling Advice
    Avoid freeze / thaw cycles.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    Nicastrin (NCSTN)
    Alternative Name
    NCSTN (NCSTN Products)
    Synonyms
    CG7012 antibody, Dmel\\CG7012 antibody, Nct antibody, Nic antibody, S5A antibody, ST96B antibody, agro antibody, dNct antibody, nic antibody, NCSTN antibody, DKFZp469O2418 antibody, APH2 antibody, 9430068N19Rik antibody, AA727311 antibody, Aph2 antibody, D1Dau13e antibody, Kiaa0253 antibody, mKIAA0253 antibody, nicastrin antibody, Nicastrin antibody, NCSTN antibody, nct antibody, ncstn antibody, CpipJ_CPIJ001617 antibody, Ncstn antibody, aph-2 antibody
    Background
    This gene encodes a type I transmembrane glycoprotein that is an integral component of the multimeric gamma-secretase complex. The encoded protein cleaves integral membrane proteins, including Notch receptors and beta-amyloid precursor protein, and may be a stabilizing cofactor required for gamma-secretase complex assembly.
    Molecular Weight
    Calculated MW: 78 kDa
    Pathways
    Notch Signaling, Neurotrophin Signaling Pathway
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