MGC82865 antibody, MGC82881 antibody, Eip75B antibody, EAR1 antibody, THRA1 antibody, THRAL antibody, ear-1 antibody, hRev antibody, A530070C09Rik antibody, R75201 antibody, REV-ERBAALPHA antibody, nuclear receptor subfamily 1 group D member 1 L homeolog antibody, nuclear receptor subfamily 1, group d, member 1 antibody, nuclear receptor subfamily 1 group D member 1 antibody, nuclear receptor subfamily 1, group D, member 1 antibody, nr1d1.L antibody, nr1d1 antibody, NR1D1 antibody, Nr1d1 antibody
Background
This gene encodes a transcription factor that is a member of the nuclear receptor subfamily 1. The encoded protein is a ligand-sensitive transcription factor that negatively regulates the expression of core clock proteins. In particular this protein represses the circadian clock transcription factor aryl hydrocarbon receptor nuclear translocator-like protein 1 (ARNTL). This protein may also be involved in regulating genes that function in metabolic, inflammatory and cardiovascular processes.