PDGFRL antibody

Catalog No. ABIN2423955

Product Details anti-PDGFRL Antibody

Target: PDGFRL (Platelet-Derived Growth Factor Receptor-Like (PDGFRL))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PDGFRL antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Affinity purification

Immunogen: Recombinant protein of human PDGFRL

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.3 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Preservative: Sodium azide

Handling Advice: Avoid freeze / thaw cycles.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

References for anti-PDGFRL antibody (ABIN2423955)

Jiang, Chen, Yuan, Ji, Liu, Wu, Tang, Shu: "Platelet-derived growth factor-D promotes colorectal cancer cell migration, invasion and proliferation by regulating Notch1 and matrix metalloproteinase-9." in: Oncology letters, Vol. 15, Issue 2, pp. 1573-1579, (2018) (PubMed).

Target Details for PDGFRL

Target: PDGFRL (Platelet-Derived Growth Factor Receptor-Like (PDGFRL))

Alternative Name: PDGFRL (PDGFRL Products)

Synonyms: zgc:56104 antibody, zgc:77677 antibody, MGC82397 antibody, PDGFRL antibody, pdgrl antibody, prlts antibody, MGC107901 antibody, PDGRL antibody, PRLTS antibody, 1110039P19Rik antibody, AV013190 antibody, platelet-derived growth factor receptor-like antibody, platelet derived growth factor receptor like L homeolog antibody, platelet derived growth factor receptor like antibody, pdgfrl antibody, pdgfrl.L antibody, PDGFRL antibody, Pdgfrl antibody

Background: This gene encodes a protein with significant sequence similarity to the ligand binding domain of platelet-derived growth factor receptor beta. Mutations in this gene, or deletion of a chromosomal segment containing this gene, are associated with sporadic hepatocellular carcinomas, colorectal cancers, and non-small cell lung cancers. This suggests this gene product may function as a tumor suppressor.

Molecular Weight: Calculated MW: 42 kDa

Pathways: Platelet-derived growth Factor Receptor Signaling