Fibulin 5 antibody

Catalog No. ABIN2425853

Product Details anti-Fibulin 5 Antibody

Target: Fibulin 5 (FBLN5)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Fibulin 5 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Purification: Affinity purification

Immunogen: Synthetic peptide of human FBLN5

Isotype: IgG

Application Details

Application Notes: IHC 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.2 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Preservative: Sodium azide

Handling Advice: Avoid freeze / thaw cycles.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Fibulin 5

Target: Fibulin 5 (FBLN5)

Alternative Name: Fibulin 5 (FBLN5 Products)

Synonyms: zgc:103575 antibody, FBLN5 antibody, MGC108414 antibody, Fibulin-5 antibody, DKFZp469K0327 antibody, ADCL2 antibody, ARCL1A antibody, ARMD3 antibody, DANCE antibody, EVEC antibody, FIBL-5 antibody, UP50 antibody, A55 antibody, fibulin 5 antibody, fbln5 antibody, FBLN5 antibody, Fbln5 antibody

Background: The protein encoded by this gene is a secreted, extracellular matrix protein containing an Arg-Gly-Asp (RGD) motif and calcium-binding EGF-like domains. It promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. It is prominently expressed in developing arteries but less so in adult vessels. However, its expression is reinduced in balloon-injured vessels and atherosclerotic lesions, notably in intimal vascular smooth muscle cells and endothelial cells. Therefore, the protein encoded by this gene may play a role in vascular development and remodeling. Defects in this gene are a cause of autosomal dominant cutis laxa, autosomal recessive cutis laxa type I (CL type I), and age-related macular degeneration type 3 (ARMD3).

NCBI Accession: NP_006320

Pathways: SARS-CoV-2 Protein Interactome