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CLDN8 antibody

CLDN8 Reactivity: Human ELISA, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2425955
  • Target See all CLDN8 Antibodies
    CLDN8 (Claudin 8 (CLDN8))
    Reactivity
    • 28
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 29
    • 2
    Rabbit
    Clonality
    • 31
    Polyclonal
    Conjugate
    • 18
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CLDN8 antibody is un-conjugated
    Application
    • 22
    • 12
    • 10
    • 5
    • 3
    • 3
    • 1
    • 1
    • 1
    ELISA, Immunohistochemistry (IHC)
    Purification
    Affinity purification
    Immunogen
    Synthetic peptide of human CLDN8
    Isotype
    IgG
    Top Product
    Discover our top product CLDN8 Primary Antibody
  • Application Notes
    IHC 1:50-1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.6 mg/mL
    Buffer
    PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
    Preservative
    Sodium azide
    Handling Advice
    Avoid freeze / thaw cycles.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    CLDN8 (Claudin 8 (CLDN8))
    Alternative Name
    Claudin 8 (CLDN8 Products)
    Synonyms
    zgc:91900 antibody, wu:fa01e05 antibody, CLDN8 antibody, AI648025 antibody, claudin 8 antibody, CLDN8 antibody, cldn8 antibody, Cldn8 antibody
    Background
    This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This protein plays important roles in the paracellular cation barrier of the distal renal tubule, and in the paracellular barrier to prevent sodium back-leakage in distal colon. Differential expression of this gene has been observed in colorectal carcinoma and renal cell tumors, and along with claudin-7, is an immunohistochemical marker for the differential diagnosis of chromophobe renal cell carcinoma and renal oncocytoma.
    NCBI Accession
    NP_955360
    Pathways
    Hepatitis C
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