CHRNA7 antibody

Catalog No. ABIN2426249

Product Details anti-CHRNA7 Antibody

Target: CHRNA7 (Cholinergic Receptor, Nicotinic, alpha 7 (Neuronal) (CHRNA7))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CHRNA7 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Purification: Affinity purification

Immunogen: Synthetic peptide of human CHRFAM7A

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:25-1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.3 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Preservative: Sodium azide

Handling Advice: Avoid freeze / thaw cycles.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for CHRNA7

Target: CHRNA7 (Cholinergic Receptor, Nicotinic, alpha 7 (Neuronal) (CHRNA7))

Alternative Name: CHRNA7 (CHRNA7 Products)

Synonyms: CHRNA7-2 antibody, NACHRA7 antibody, dZ70B1.1 antibody, Acra7 antibody, alpha7 antibody, BTX antibody, NARAD antibody, nAChRa7 antibody, CHRNA7 antibody, cholinergic receptor nicotinic alpha 7 subunit antibody, neuronal acetylcholine receptor subunit alpha-7 antibody, cholinergic receptor, nicotinic, alpha 7 (neuronal) antibody, cholinergic receptor, nicotinic, alpha polypeptide 7 antibody, cholinergic receptor, nicotinic, alpha 7 antibody, CHRNA7 antibody, LOC100374356 antibody, chrna7 antibody, Chrna7 antibody, LOC100060521 antibody

Background: 7nAChR,a7 nicotinic acetylcholine receptor,acetylcholine receptor,neuronal nicotinic,alpha-7 subunit,ACHA7,AChR,Acra7,alpha 7 neuronal nicotinic acetylcholine receptor,alpha-7 nicotinic cholinergic receptor subunit,alpha7,cholinergic receptor,neuronal nicotinic,alpha polypeptide 7,cholinergic receptor,nicotinic,alpha 7 (neuronal),cholinergic receptor,nicotinic,alpha 7,cholinergic receptor,nicotinic,alpha polypeptide 7,CHRNA7,CHRNA7-2,NACHRA7,neuronal acetylcholine receptor protein,alpha-7 chain,Neuronal acetylcholine receptor subunit alpha-7,The nicotinic acetylcholine receptors (nAChRs) are members of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. The family member CHRNA7, which is located on chromosome 15 in a region associated with several neuropsychiatric disorders, is partially duplicated and forms a hybrid with a novel gene from the family with sequence similarity 7 (FAM7A). Alternative splicing has been observed, and two variants exist, for this hybrid gene. The N-terminally truncated products predicted by the largest open reading frames for each variant would lack the majority of the neurotransmitter-gated ion-channel ligand binding domain but retain the transmembrane region that forms the ion channel. Although current evidence supports transcription of this hybrid gene, translation of the nicotinic acetylcholine receptor-like protein-encoding open reading frames has not been confirmed.

Molecular Weight: Calculated MW: 46 kDa

NCBI Accession: NP_683709

Pathways: Synaptic Membrane