AKR1C1 antibody

Catalog No. ABIN2426547

Product Details anti-AKR1C1 Antibody

Target: AKR1C1 (DDH) (Dihydrodiol Dehydrogenase (DDH))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AKR1C1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Purification: Affinity purification

Immunogen: Synthetic peptide of human AKR1C1

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Preservative: Sodium azide

Handling Advice: Avoid freeze / thaw cycles.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for AKR1C1

Target: AKR1C1 (DDH) (Dihydrodiol Dehydrogenase (DDH))

Alternative Name: AKR1C1 (DDH Products)

Synonyms: 2-ALPHA-HSD antibody, 20-ALPHA-HSD antibody, C9 antibody, DD1 antibody, DD1/DD2 antibody, DDH antibody, DDH1 antibody, H-37 antibody, HAKRC antibody, HBAB antibody, MBAB antibody, aldo-keto reductase family 1 member C1 antibody, aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase) antibody, AKR1C1 antibody

Background: 2-dihydrobenzene-1,2-diol dehydrogenase,20 alpha (3 alpha) hydroxysteroid dehydrogenase,20 ALPHA HSD,20 alpha hydroxysteroid dehydrogenase,20-alpha-HSD,20-alpha-hydroxysteroid dehydrogenase,20ALPHAHSD,2ALPHAHSD,AK1C1,AK1C1,AKR1C1,Aldo keto reductase family 1 member C1,aldo-keto reductase C,Aldo-keto reductase family 1 member C1,Aldo-keto reductase family,1 member 1,C9,Chlordecone reductase homolog,Chlordecone reductase homolog HAKRC,DD1,DD1/DD2,DDH,DDH1,Dihydrodiol dehydrogenase 1,Dihydrodiol dehydrogenase 1/2,dihydrodiol dehydrogenase 1,20-alpha (3-alpha)-hydroxysteroid dehydrogenase,dihydrodiol dehydrogenase isoform DD1,Dihydrodiol dehydrogenase,type 1,H37,HAKRC,HBAB,Hepatic dihydrodiol dehydrogenase,High affinity hepatic bile acid-binding protein,High-affinity hepatic bile acid-binding protein,Indanol dehydrogenase,MBAB,MGC8954,Trans-1,Trans-1,2 dihydrobenzene 1,2 diol dehydrogenase,Type II 3 alpha hydroxysteroid dehydrogenase,This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reaction of progesterone to the inactive form 20-alpha-hydroxy-progesterone. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14.

Molecular Weight: Calculated MW: 37 kDa

NCBI Accession: NP_001344

Pathways: Steroid Hormone Biosynthesis, C21-Steroid Hormone Metabolic Process