PTPRM antibody

Catalog No. ABIN2426853

Product Details anti-PTPRM Antibody

Target: PTPRM (Protein Tyrosine Phosphatase, Receptor Type, M (PTPRM))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PTPRM antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Purification: Affinity purification

Immunogen: Synthetic peptide of human PTPRM

Isotype: IgG

Application Details

Application Notes: IHC 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.4 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Preservative: Sodium azide

Handling Advice: Avoid freeze / thaw cycles.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PTPRM

Target: PTPRM (Protein Tyrosine Phosphatase, Receptor Type, M (PTPRM))

Alternative Name: PTPRM (PTPRM Products)

Synonyms: cb984 antibody, ptprm antibody, zgc:110218 antibody, PTPRM antibody, p-ptp-mu antibody, ptprl1 antibody, r-ptpu antibody, rptpm antibody, rptpu antibody, PTPRL1 antibody, R-PTP-MU antibody, RPTPM antibody, RPTPU antibody, hR-PTPu antibody, RPTPmu antibody, mKIAA4044 antibody, protein tyrosine phosphatase, receptor type, M, a antibody, protein tyrosine phosphatase, receptor type M antibody, protein tyrosine phosphatase, receptor type, M, b antibody, receptor-type tyrosine-protein phosphatase mu antibody, protein tyrosine phosphatase, receptor type, M antibody, ptprma antibody, PTPRM antibody, ptprmb antibody, ptprm antibody, LOC100550127 antibody, LOC100564083 antibody, Ptprm antibody

Background: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains a meprin-A5 antigen-PTP mu (MAM) domain, an Ig-like domain and four fibronectin type III-like repeats. This PTP has been shown to mediate cell-cell aggregation through the interaction with another molecule of this PTP on an adjacent cell. This PTP can interact with scaffolding protein RACK1/GNB2L1, whicHuman, Mouseay be necessary for the downstream signaling in response to cell-cell adhesion. Alternative splicing results in multiple transcripts encoding distinct isoforms.

NCBI Accession: NP_002836