TGFBR1 antibody

Catalog No. ABIN2426967

Product Details anti-TGFBR1 Antibody

Target: TGFBR1 (Transforming Growth Factor, beta Receptor 1 (TGFBR1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TGFBR1 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Purification: Affinity purification

Immunogen: Synthetic peptide of human TGFBR1

Isotype: IgG

Application Details

Application Notes: IHC 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.3 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Preservative: Sodium azide

Handling Advice: Avoid freeze / thaw cycles.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for TGFBR1

Target: TGFBR1 (Transforming Growth Factor, beta Receptor 1 (TGFBR1))

Alternative Name: TGF beta Receptor I (TGFBR1 Products)

Synonyms: AAT5 antibody, ACVRLK4 antibody, ALK-5 antibody, ALK5 antibody, LDS1A antibody, LDS2A antibody, MSSE antibody, SKR4 antibody, TGFR-1 antibody, aat5 antibody, acvrlk4 antibody, alk-5 antibody, alk5 antibody, lds1a antibody, lds2a antibody, skr4 antibody, tgfr-1 antibody, TGFBR1 antibody, x-trr1 antibody, AU017191 antibody, Alk-5 antibody, TbetaR-I antibody, TbetaRI antibody, Alk5 antibody, Skr4 antibody, Tgfr-1 antibody, tbetaR-I antibody, tgfbr1 antibody, zgc:123263 antibody, transforming growth factor beta receptor 1 antibody, transforming growth factor beta receptor I antibody, transforming growth factor beta receptor I S homeolog antibody, transforming growth factor, beta receptor I antibody, transforming growth factor, beta receptor 1 antibody, transforming growth factor, beta receptor 1 a antibody, TGFBR1 antibody, tgfbr1 antibody, tgfbr1.S antibody, Tgfbr1 antibody, tgfbr1a antibody

Background: The protein encoded by this gene forms a heteromeric complex with type II TGF-beta receptors when bound to TGF-beta, transducing the TGF-beta signal from the cell surface to the cytoplasm. The encoded protein is a serine/threonine protein kinase. Mutations in this gene have been associated with Loeys-Dietz aortic aneurysm syndrome (LDAS). Multiple transcript variants encoding different isoforms have been found for this gene.

NCBI Accession: NP_001124388

Pathways: Growth Factor Binding