IL18BP antibody

Catalog No. ABIN2427697

Product Details anti-IL18BP Antibody

Target: IL18BP (Interleukin 18 Binding Protein (IL18BP))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL18BP antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Purification: Affinity purification

Immunogen: Recombinant protein of human IL18BP

Isotype: IgG

Application Details

Application Notes: IHC 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.4 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Preservative: Sodium azide

Handling Advice: Avoid freeze / thaw cycles.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for IL18BP

Target: IL18BP (Interleukin 18 Binding Protein (IL18BP))

Alternative Name: IL18BP (IL18BP Products)

Synonyms: IL18BP antibody, IL-18BP antibody, Igifbp antibody, MC54L antibody, IL18BPa antibody, interleukin 18 binding protein antibody, IL18BP antibody, Il18bp antibody

Background: The protein encoded by this gene functions as an inhibitor of the proinflammatory cytokine, IL18. It binds IL18, prevents the binding of IL18 to its receptor, and thus inhibits IL18-induced IFN-gamma production, resulting in reduced T-helper type 1 immune responses. This protein is constitutively expressed and secreted in mononuclear cells. Elevated level of this protein is detected in the intestinal tissues of patients with Crohn's disease. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.