MSH4 antibody

Catalog No. ABIN2428425

Product Details anti-MSH4 Antibody

Target: MSH4 (MutS Homolog 4 (E. Coli) (MSH4))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MSH4 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Purification: Affinity purification

Immunogen: Recombinant protein of human MSH4

Isotype: IgG

Application Details

Application Notes: IHC 1:100-1:300

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Preservative: Sodium azide

Handling Advice: Avoid freeze / thaw cycles.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for MSH4

Target: MSH4 (MutS Homolog 4 (E. Coli) (MSH4))

Alternative Name: MSH4 (MSH4 Products)

Synonyms: MSH4 antibody, 4930485C04Rik antibody, AV144863 antibody, mMsh4 antibody, mutS homolog 4 antibody, mutS protein homolog 4 antibody, Msh4 antibody, MSH4 antibody, msh4 antibody, LOC575381 antibody, LOC100639599 antibody

Background: This gene encodes a member of the DNA mismatch repair mutS family. This member is a meiosis-specific protein that is not involved in DNA mismatch correction, but is required for reciprocal recombination and proper segregation of homologous chromosomes at meiosis I. This protein and MSH5 form a heterodimer which binds uniquely to a Holliday Junction and its developmental progenitor, thus provoking ADP-ATP exchange, and stabilizing the interaction between parental chromosomes during meiosis double-stranded break repair.