STK40 antibody

Catalog No. ABIN2429423

Product Details anti-STK40 Antibody

Target: STK40 (serine/threonine Kinase 40 (STK40))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This STK40 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Purification: Affinity purification

Immunogen: Recombinant protein of human STK40

Isotype: IgG

Application Details

Application Notes: IHC 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.3 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Preservative: Sodium azide

Handling Advice: Avoid freeze / thaw cycles.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for STK40

Target: STK40 (serine/threonine Kinase 40 (STK40))

Alternative Name: STK40 (STK40 Products)

Synonyms: cb988 antibody, fd99h11 antibody, wu:fd99h11 antibody, NV14115 antibody, DKFZp459J1924 antibody, RP11-268J15.4 antibody, SHIK antibody, SgK495 antibody, 2310004N11Rik antibody, AI428792 antibody, Lyk4 antibody, RGD1307310 antibody, serine/threonine kinase 40 antibody, serine/threonine kinase 40 L homeolog antibody, STK40 antibody, stk40 antibody, LOC100123745 antibody, Stk40 antibody, stk40.L antibody

Background: STK40 (Serine/threonine-protein kinase 40), also known as Sugen kinase 495, is a 435 amino acid protein kinase that may be a negative regulator of NFκB and p53-mediated gene expression. Localized to both the cytoplasm and the nucleus, STK40 is ubiquitously expressed. STK40 has a central serine/threonine protein kinase domain and is homologous to TRB-3, a protein that regulates activation of MAP kinases and inhibits NFκB-mediated gene transcription. Similarly, overexpression of STK40 inhibits NFκB activation triggered by TNF and also inhibits p53-mediated transcription. There are four named isoforms of STK40 that are produced as a result of alternative splicing.