CLPS antibody

Catalog No. ABIN2429797

Product Details anti-CLPS Antibody

Target: CLPS (Colipase, Pancreatic (CLPS))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CLPS antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Purification: Affinity purification

Immunogen: Recombinant protein of human CLPS

Isotype: IgG

Application Details

Application Notes: IHC 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.4 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Preservative: Sodium azide

Handling Advice: Avoid freeze / thaw cycles.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for CLPS

Target: CLPS (Colipase, Pancreatic (CLPS))

Alternative Name: CLPS (CLPS Products)

Synonyms: CLPS antibody, 2200003J09Rik antibody, COLQ antibody, colipase antibody, colipase, pancreatic antibody, CLPS antibody, Clps antibody

Background: The protein encoded by this gene is a cofactor needed by pancreatic lipase for efficient dietary lipid hydrolysis. It binds to the C-terminal, non-catalytic domain of lipase, thereby stabilizing an active conformation and considerably increasing the overall hydrophobic binding site. The gene product allows lipase to anchor noncovalently to the surface of lipid micelles, counteracting the destabilizing influence of intestinal bile salts. This cofactor is only expressed in pancreatic acinar cells, suggesting regulation of expression by tissue-specific elements. Three transcript variants encoding different isoforms have been found for this gene.

Pathways: Lipid Metabolism