DEFA4 antibody

Catalog No. ABIN2432935

Product Details anti-DEFA4 Antibody

Target: DEFA4 (Defensin, alpha 4, Corticostatin (DEFA4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DEFA4 antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA

Purification: Affinity purification

Immunogen: Synthetic peptide of human DEFA4

Isotype: IgG

Application Details

Application Notes: IHC 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.9 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Preservative: Sodium azide

Handling Advice: Avoid freeze / thaw cycles.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for DEFA4

Target: DEFA4 (Defensin, alpha 4, Corticostatin (DEFA4))

Alternative Name: DEFA4 (DEFA4 Products)

Synonyms: DEF4 antibody, HNP-4 antibody, HP-4 antibody, HP4 antibody, DEFA4 antibody, Crp4 antibody, Defa28 antibody, Defcr4 antibody, defensin alpha 4 antibody, defensin, alpha 4, corticostatin antibody, defensin, alpha, 4 antibody, DEFA4 antibody, Defa4 antibody

Background: Defensins are a family of microbicidal and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. Several alpha defensin genes are clustered on chromosome 8. This gene differs from other genes of this family by an extra 83-base segment that is apparently the result of a recent duplication within the coding region. The protein encoded by this gene, defensin, alpha 4, is found in the neutrophils, it exhibits corticostatic activity and inhibits corticotropin stimulated corticosterone production.

NCBI Accession: NP_001916