Integrin beta 7 antibody

Catalog No. ABIN2433217

Product Details anti-Integrin beta 7 Antibody

Target: Integrin beta 7 (ITGB7)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Integrin beta 7 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Purification: Affinity purification

Immunogen: Synthetic peptide of human ITGB7

Isotype: IgG

Application Details

Application Notes: IHC 1:100-1:300

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.7 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Preservative: Sodium azide

Handling Advice: Avoid freeze / thaw cycles.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Integrin beta 7

Target: Integrin beta 7 (ITGB7)

Alternative Name: ITGB7 (ITGB7 Products)

Synonyms: Ly69 antibody, integrin beta 7 antibody, integrin subunit beta 7 antibody, integrin, beta 7 antibody, Itgb7 antibody, ITGB7 antibody

Background: This gene encodes a protein that is a member of the integrin superfamily. Members of this family are adhesion receptors that function in signaling from the extracellular matrix to the cell. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. The encoded protein forms dimers with an alpha4 chain or an alphaE chain and plays a role in leukocyte adhesion. Dimerization with alpha4 forms a homing receptor for migration of lymphocytes to the intestinal mucosa and Peyer's patches. Dimerization with alphaE permits binding to the ligand epithelial cadherin, a calcium-dependent adhesion molecule. Alternate splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known.

NCBI Accession: NP_000880

Pathways: Integrin Complex