PNN antibody

Catalog No. ABIN2433597

Product Details anti-PNN Antibody

Target: PNN (Pinin, Desmosome Associated Protein (PNN))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PNN antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Purification: Affinity purification

Immunogen: Synthetic peptide of human PNN

Isotype: IgG

Application Details

Application Notes: IHC 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.2 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Preservative: Sodium azide

Handling Advice: Avoid freeze / thaw cycles.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PNN

Target: PNN (Pinin, Desmosome Associated Protein (PNN))

Alternative Name: PNN (PNN Products)

Synonyms: DRS antibody, DRSP antibody, SDK3 antibody, memA antibody, wu:fb24d03 antibody, pnn antibody, MGC88923 antibody, PNN antibody, AU045199 antibody, D12Ertd512e antibody, CG8383 antibody, Dmel\\CG8383 antibody, dPnn antibody, pinin, desmosome associated protein antibody, pinin antibody, Pinin antibody, PNN antibody, Pnn antibody, pnn antibody, LOC100380709 antibody

Background: Pinin is a desmosomal associated protein involved with the maintenance of cell to cell adhesion of the epithelium. Pinin is a widespread protein and has been shown to play an important role in cell adhesion through its interaction with nuclear complexes. Pinin is also involved in pre-mRNA splicing through its interactions with a C-terminal RS domain of Cyclophilin G, a Moca type nuclear cyclophilin. Pinin becomes nuclear during the early stages of embryonic development and remains so throughout the entire period. Defects or lack of Pinin can be lethal at perinatal stages and causes defects in the cardiac outflow tract, axial skeleton, palate and dorsal dermis.

NCBI Accession: NP_002678