ADPRHL2 antibody

Catalog No. ABIN2434150

Product Details anti-ADPRHL2 Antibody

Target: ADPRHL2 (ADP-Ribosylhydrolase Like 2 (ADPRHL2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ADPRHL2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antigen affinity purification

Immunogen: Synthetic peptide of human ADPRHL2

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Handling Advice: Avoid freeze / thaw cycles.

Storage: -20 °C/-80 °C

Storage Comment: Store at -20°C (regular) and -80°C (long term).

Target Details for ADPRHL2

Target: ADPRHL2 (ADP-Ribosylhydrolase Like 2 (ADPRHL2))

Alternative Name: ADPRHL2 (ADPRHL2 Products)

Synonyms: ARH3 antibody, AI836109 antibody, Arh3 antibody, ADP-ribosylhydrolase like 2 antibody, Adprhl2 antibody, ADPRHL2 antibody

Background: This gene encodes a member of the ADP-ribosylglycohydrolase family. The encoded enzyme catalyzes the removal of ADP-ribose from ADP-ribosylated proteins. This enzyme localizes to the mitochondria, in addition to the nucleus and cytoplasm. Poly(ADP-ribose) synthesized after DNA damage is only present transiently and is rapidly degraded by poly(ADP-ribose) glycohydrolase. Poly(ADP-ribose) metabolism may be required for maintenance of the normal function of neuronal cells. Generates ADP-ribose from poly-(ADP-ribose), but does not hydrolyze ADP-ribose-arginine, -cysteine, -diphthamide, or -asparagine bonds. Due to catalytic inactivity of PARG mitochondrial isoforms, ARH3 is the only PAR hydrolyzing enzyme in mitochondria.
Synonyms: ARH3

Molecular Weight: Calculated MW: 39 kDa