CACNA1C antibody

Catalog No. ABIN2434364

Product Details anti-CACNA1C Antibody

Target: CACNA1C (Calcium Channel, Voltage-Dependent, L Type, alpha 1C Subunit (CACNA1C))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CACNA1C antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA

Purification: Affinity purification

Immunogen: Synthetic peptide of human CACNA1C

Isotype: IgG

Application Details

Application Notes: IHC 1:25-1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.6 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Preservative: Sodium azide

Handling Advice: Avoid freeze / thaw cycles.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for CACNA1C

Target: CACNA1C (Calcium Channel, Voltage-Dependent, L Type, alpha 1C Subunit (CACNA1C))

Alternative Name: Cav1.2 (CACNA1C Products)

Synonyms: CACH2 antibody, CACN2 antibody, CACNL1A1 antibody, CCHL1A1 antibody, CaV1.2 antibody, LQT8 antibody, TS antibody, Cav1.2 antibody, Cchl1a1 antibody, MBC antibody, MELC-CC antibody, RATIVS302 antibody, isl antibody, C-LTCC antibody, CHCACHA1C antibody, ICA antibody, cav1.2 antibody, ca(v)1.2 antibody, CAV1.2 antibody, BCR antibody, rbc antibody, calcium voltage-gated channel subunit alpha1 C antibody, calcium channel, voltage-dependent, L type, alpha 1C subunit antibody, voltage-dependent L-type calcium channel subunit alpha-1C antibody, calcium channel, voltage-dependent, L type, alpha 1C subunit S homeolog antibody, Red blood cell count antibody, RNA, 7SL, cytoplasmic 263, pseudogene antibody, CACNA1C antibody, Cacna1c antibody, cacna1c antibody, LOC100442085 antibody, cacna1c.S antibody, RBC antibody, RN7SL263P antibody

Background: This gene encodes an alpha-1 subunit of a voltage-dependent calcium channel. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization. The alpha-1 subunit consists of 24 transmembrane segments and forms the pore through which ions pass into the cell. The calcium channel consists of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. There are multiple isoforms of each of these proteins, either encoded by different genes or the result of alternative splicing of transcripts. The protein encoded by this gene binds to and is inhibited by dihydropyridine. Alternative splicing results in many transcript variants encoding different proteins. Some of the predicted proteins may not produce functional ion channel subunits.

NCBI Accession: NP_955630

Pathways: Hormone Transport, Carbohydrate Homeostasis