IL5RA antibody

Catalog No. ABIN2434823

Product Details anti-IL5RA Antibody

Target: IL5RA (Interleukin 5 Receptor, alpha (IL5RA))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL5RA antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Purification: Affinity purification

Immunogen: Synthetic peptide of human IL5RA

Isotype: IgG

Application Details

Application Notes: WB 1:200-1:1000, IHC 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.8 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Preservative: Sodium azide

Handling Advice: Avoid freeze / thaw cycles.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for IL5RA

Target: IL5RA (Interleukin 5 Receptor, alpha (IL5RA))

Alternative Name: IL5RA (IL5RA Products)

Synonyms: MGC86517 antibody, IL5RA antibody, il5r antibody, cdw125 antibody, hsil5r3 antibody, gpIL-5ra antibody, CD125 antibody, CDw125 antibody, HSIL5R3 antibody, IL5R antibody, Il5r antibody, interleukin 5 receptor subunit alpha L homeolog antibody, interleukin 5 receptor subunit alpha antibody, interleukin 5 receptor, alpha antibody, il5ra.L antibody, IL5RA antibody, il5ra antibody, Il5ra antibody

Background: The protein encoded by this gene is an interleukin 5 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL5 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL5. This protein has been found to interact with syndecan binding protein (syntenin), which is required for IL5 mediated activation of the transcription factor SOX4. Several alternatively spliced transcript variants encoding four distinct isoforms have been reported.

Molecular Weight: Calculated MW: 48 kDa

NCBI Accession: NP_000555

Pathways: JAK-STAT Signaling