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TP53INP1 antibody

TP53INP1 Reactivity: Human WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2435140
  • Target See all TP53INP1 Antibodies
    TP53INP1 (Tumor Protein P53 Inducible Nuclear Protein 1 (TP53INP1))
    Reactivity
    • 56
    • 29
    • 13
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 63
    Rabbit
    Clonality
    • 53
    • 9
    Polyclonal
    Conjugate
    • 26
    • 6
    • 6
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This TP53INP1 antibody is un-conjugated
    Application
    • 44
    • 34
    • 31
    • 12
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Purification
    Affinity purification
    Immunogen
    Synthetic peptide of human TP53INP1
    Isotype
    IgG
    Top Product
    Discover our top product TP53INP1 Primary Antibody
  • Application Notes
    WB 1:200-1:1000, IHC 1:50-1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.5 mg/mL
    Buffer
    PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
    Preservative
    Sodium azide
    Handling Advice
    Avoid freeze / thaw cycles.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    TP53INP1 (Tumor Protein P53 Inducible Nuclear Protein 1 (TP53INP1))
    Alternative Name
    TP53INP1 (TP53INP1 Products)
    Synonyms
    cb1036 antibody, wu:fb70a09 antibody, wu:fi13h08 antibody, zgc:158431 antibody, TP53INP1 antibody, 2700057G22Rik antibody, SIP antibody, SIP18 antibody, SIP27 antibody, Stinp antibody, Teap antibody, TP53DINP1 antibody, TP53INP1A antibody, TP53INP1B antibody, p53DINP1 antibody, Trp53inp1 antibody, tumor protein p53 inducible nuclear protein 1 antibody, tumor protein p53 inducible nuclear protein 1 S homeolog antibody, transformation related protein 53 inducible nuclear protein 1 antibody, TP53INP1 antibody, tp53inp1.S antibody, tp53inp1 antibody, Trp53inp1 antibody, Tp53inp1 antibody
    Background
    TP53INP1 (tumor protein p53-inducible nuclear protein 1), also known as p53DINP1, SIP or Teap, is a 240 amino acid protein that localizes to nuclear bodies and exists as two alternatively spliced isoforms, designated p53DINP1a and p53DINP1b. Expressed ubiquitously with higher expression in testis, pancreas and spleen tissue, TP53INP1 functions in response to double-stranded DNA breaks and regulates p53-mediated apoptosis, specifically by phosphorylating human p53 at Ser 46, an event that leads to cell death. Additionally, TP53INP1 is thought to interact with p73 and may be involved in the regulation of p73-controlled cell cycle progression. TP53INP1 expression is downregulated in pancreatic ductal adenocarcinomas, suggesting that, via its ability to induce cell death, TP53INP1 plays a role in tumor suppression.
    Molecular Weight
    Calculated MW: 27 kDa
    NCBI Accession
    NP_150601
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