ROBO4 antibody (full length)

Catalog No. ABIN2443871

Product Details anti-ROBO4 Antibody

Target: ROBO4 (Roundabout, Axon Guidance Receptor, Homolog 4 (ROBO4))

Binding Specificity: full length

Reactivity: Human, Mouse

Host: Guinea Pig

Clonality: Polyclonal

Conjugate: This ROBO4 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS)

Specificity: The antibody recognizes Robo-4 protein.

Immunogen: Recombinant protein

Isotype: IgG1

Application Details

Application Notes: If reconstituted with deionized water in 100 µl: WB 1:1000; FACS 1:300.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Preservative: Without preservative

Storage: 4 °C/-20 °C/-80 °C

Storage Comment: Lyophilized antibodies can be kept at 4ºC for up to 3 months and should be kept at -20ºC for long-term storage (2 years). To avoid freeze-thaw cycles, reconstituted antibodies should be aliquoted before freezing for long-term (1 year) storage (-80ºC) or kept at 4ºC for short-term usage (2 months). For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made with the assay buffer. After the maximum long-term storage period (2 years lyophilized or 1 year reconstituted) antibodies should be tested in your assay with a standard sample to verify if you have noticed any decrease in their efficacy. To limit antibody loss or degradation, BSA (final concentration 1%) and sodium azide (final concentration 0.02%) can be added to the suggested first dilution. It is important to first verify if those preservatives are compatible with your assay.

Target Details for ROBO4

Target: ROBO4 (Roundabout, Axon Guidance Receptor, Homolog 4 (ROBO4))

Alternative Name: Robo4 (ROBO4 Products)

Synonyms: ECSM4 antibody, MRB antibody, 1200012D01Rik antibody, AI593217 antibody, sc:d0823 antibody, wu:fa16f09 antibody, roundabout guidance receptor 4 antibody, roundabout, axon guidance receptor, homolog 4 (Drosophila) antibody, ROBO4 antibody, Robo4 antibody, robo4 antibody

Background: The Robo (Roundabout) family of receptors is known for its guidance role during development. Studies have shown that one of the family members, Robo4, is specifically expressed in the vascular endothelium and may provide directional cues to migrating endothelial cells. Recent evidence shows that Robo4-deficient mice have increased angiogenesis, suggesting that Robo4 may play a role in restricting vascular sprouting.

UniProt: Q6EIG7