PSMD13 antibody (full length)

Catalog No. ABIN2452116

Product Details anti-PSMD13 Antibody

Target: PSMD13 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 13 (PSMD13))

Binding Specificity: full length

Reactivity: Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PSMD13 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Cross-Reactivity (Details): Not tested in other species.

Characteristics: IgG fraction of rabbit polyclonal antibody against Rpn9. GST antibody was removed by passing through GST affinity column.

Purification: Affinity purified

Immunogen: GST-full length Rpn9 fusion protein expressed in E. coli

Isotype: IgG

Application Details

Application Notes: 1) Western blotting: 1/1,000~1/2,000
2) Immunoprecipitation

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, 1 mg/mL BSA, 0.09 % sodium azide, 50 % glycerol

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Upon arrival centrifuge briefly, aliquot and store at -20 C

References for anti-PSMD13 antibody (ABIN2452116)

Takeuchi, Fujimuro, Yokosawa, Tanaka, Toh-e: "Rpn9 is required for efficient assembly of the yeast 26S proteasome." in: Molecular and cellular biology, Vol. 19, Issue 10, pp. 6575-84, (2000) (PubMed).

Target Details for PSMD13

Target: PSMD13 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 13 (PSMD13))

Alternative Name: Rpn9 (PSMD13 Products)

Synonyms: HSPC027 antibody, Rpn9 antibody, S11 antibody, p40.5 antibody, zgc:56377 antibody, zgc:77482 antibody, MGC84231 antibody, MGC69415 antibody, DDBDRAFT_0186342 antibody, DDBDRAFT_0233004 antibody, DDB_0186342 antibody, DDB_0233004 antibody, proteasome 26S subunit, non-ATPase 13 antibody, proteasome (prosome, macropain) 26S subunit, non-ATPase, 13 antibody, proteasome 26S subunit, non-ATPase 13 S homeolog antibody, 26S proteasome non-ATPase regulatory subunit 13 antibody, PSMD13 antibody, Psmd13 antibody, psmd13 antibody, psmd13.S antibody, psmD13 antibody

Background: Background: The 26 S proteasome is a protein complex with a molecular mass of 2,000 kDa. It is essential not only for eliminating damaged or misfolded proteins but also for degrading short lived regulatory proteins involved in cell cycle regulation, DNA repair, signal transduction, apoptosis, and metabolic regulation. The 26S proteasome is composed of the 20S core particle (CP) and the 19S regulatory particle (RP). The RP is further subdivided into lid and base sub-complexes. Rpn9 is one of the non-ATPase subunits of lid. Rpn9 plays a key role in facilitating the assembly of the 26S proteasome or in stabilizing the structure of the 26S proteasome. Rpn9 null mutant is temperature sensitive and exhibits cell cycle and proteasome assembly defects.

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Ubiquitin Proteasome Pathway