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TPSG1 antibody (AA 20-283)

TPSG1 Reactivity: Human WB Host: Mouse Monoclonal 3F2 unconjugated
Catalog No. ABIN2734409
  • Target See all TPSG1 Antibodies
    TPSG1 (Tryptase gamma 1 (TPSG1))
    Binding Specificity
    • 3
    • 2
    • 1
    AA 20-283
    Reactivity
    • 8
    • 1
    • 1
    Human
    Host
    • 5
    • 3
    Mouse
    Clonality
    • 5
    • 3
    Monoclonal
    Conjugate
    • 5
    • 3
    This TPSG1 antibody is un-conjugated
    Application
    • 8
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Characteristics
    Homo sapiens tryptase gamma 1 (TPSG1)
    Purification
    Purified from mouse ascites fluids by affinity chromatography
    Immunogen
    Human recombinant protein fragment corresponding to amino acids 20-283 of human TPSG1(NP_036599) produced in E.coli.
    Clone
    3F2
    Isotype
    IgG1
    Top Product
    Discover our top product TPSG1 Primary Antibody
  • Application Notes
    WB 1:2000,
    Comment

    The concentration of the product may vary between diferrent lots.

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.5-1.0 mg/mL
    Buffer
    PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
  • Target
    TPSG1 (Tryptase gamma 1 (TPSG1))
    Alternative Name
    TPSG1 (TPSG1 Products)
    Synonyms
    mpn antibody, PRSS31 antibody, TMT antibody, trpA antibody, Prss31 antibody, Tmt antibody, tryptase gamma 1 S homeolog antibody, tryptase gamma 1 antibody, tpsg1.S antibody, tpsg1 antibody, TPSG1 antibody, Tpsg1 antibody
    Background
    Tryptases comprise a family of trypsin-like serine proteases, the peptidase family S1. Tryptases are enzymatically active only as heparin-stabilized tetramers, and they are resistant to all known endogenous proteinase inhibitors. Several tryptase genes are clustered on chromosome 16p13.3. There is uncertainty regarding the number of genes in this cluster. Currently four functional genes - alpha I, beta I, beta II and gamma I - have been identified. And beta I has an allelic variant named alpha II, beta II has an allelic variant beta III, also gamma I has an allelic variant gamma II. Beta tryptases appear to be the main isoenzymes expressed in mast cells, whereas in basophils, alpha-tryptases predominant. This gene differs from other members of the tryptase gene family in that it has C-terminal hydrophobic domain, which may serve as a membrane anchor. Tryptases have been implicated as mediators in the pathogenesis of asthma and other allergic and inflammatory disorders. COMPLETENESS: complete on the 3' end.
    Molecular Weight
    32 kDa
    Gene ID
    25823
    NCBI Accession
    NM_012467
    HGNC
    25823
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