HLCS antibody

Catalog No. ABIN2716652

Product Details anti-HLCS Antibody

Target: HLCS (Biotin-Protein Ligase (HLCS))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This HLCS antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)

Characteristics: Homo sapiens holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase) (HLCS), transcript variant 1

Purification: Purified from mouse ascites fluids by affinity chromatography

Immunogen: Full length human recombinant protein of human HLCS(NP_000402) produced in HEK293T cell.

Clone: 1E4

Isotype: IgG1

Application Details

Application Notes: WB 1:2000, IHC 1:150, FLOW 1:100,

Comment:

The concentration of the product may vary between diferrent lots.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5-1.0 mg/mL

Buffer: PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for HLCS

Target: HLCS (Biotin-Protein Ligase (HLCS))

Alternative Name: HLCS (HLCS Products)

Synonyms: 410I21.SP6 antibody, D16Jhu34 antibody, HCS antibody, RGD1565360 antibody, holocarboxylase synthetase (biotin- [propriony-Coenzyme A-carboxylase (ATP-hydrolysing)] ligase) antibody, holocarboxylase synthetase antibody, Hlcs antibody, HLCS antibody

Background: This gene encodes an enzyme that catalyzes the binding of biotin to carboxylases and histones. The protein plays an important role in gluconeogenesis, fatty acid synthesis and branched chain amino acid catabolism. Defects in this gene are the cause of holocarboxylase synthetase deficiency. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Molecular Weight: 80.6 kDa

Gene ID: 3141

NCBI Accession: NM_000411

HGNC: 3141