L3MBTL2 antibody

Catalog No. ABIN2457889

Product Details anti-L3MBTL2 Antibody

Target: L3MBTL2 (Lethal(3) Malignant Brain Tumor-Like Protein 2 (L3MBTL2))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This L3MBTL2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human L3MBTL2.

Application Details

Application Notes: L3MBTL2 antibody can be used for detection of L3MBTL2 by ELISA at 1:312500. L3MBTL2 antibody can be used for detection of L3MBTL2 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store L3MBTL2 antibody at -20 °C.

Target Details for L3MBTL2

Target: L3MBTL2 (Lethal(3) Malignant Brain Tumor-Like Protein 2 (L3MBTL2))

Alternative Name: L3MBTL2 (L3MBTL2 Products)

Synonyms: L3MBTL2 antibody, im:7137244 antibody, wu:fb04e09 antibody, zgc:66491 antibody, H-l(3)mbt-l antibody, L3MBT antibody, 4732493N06Rik antibody, M4mbt antibody, L3MBTL2 polycomb repressive complex 1 subunit antibody, L3MBTL2, polycomb repressive complex 1 subunit antibody, l(3)mbt-like 2 (Drosophila) antibody, L3MBTL2 antibody, l3mbtl2 antibody, L3mbtl2 antibody

Background: L3MBTL2 contains 1 FCS-type zinc finger and 4 MBT repeats. It is putative Polycomb group (PcG) protein. PcG proteins maintain the transcriptionally repressive state of genes, probably via a modification of chromatin, rendering it heritably changed in its expressibility. Its association with a chromatin remodeling complex suggests that it may contribute to prevent expression of genes that trigger the cell into mitosis.

Molecular Weight: 69 kDa

Gene ID: 83746

NCBI Accession: NP_001003689

UniProt: Q969R5