EYA1 antibody

Catalog No. ABIN2457953

Product Details anti-EYA1 Antibody

Target: EYA1 (Eyes Absent Homolog 1 (EYA1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EYA1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human EYA1.

Application Details

Application Notes: EYA1 antibody can be used for detection of EYA1 by ELISA at 1:312500. EYA1 antibody can be used for detection of EYA1 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store EYA1 antibody at -20 °C.

Target Details for EYA1

Target: EYA1 (Eyes Absent Homolog 1 (EYA1))

Alternative Name: EYA1 (EYA1 Products)

Synonyms: EYA1 antibody, bop antibody, bor antibody, XEya1 antibody, wu:fc13c10 antibody, zgc:100770 antibody, BOP antibody, BOR antibody, BOS1 antibody, EYA transcriptional coactivator and phosphatase 1 antibody, EYA transcriptional coactivator and phosphatase 1 L homeolog antibody, EYA1 antibody, eya1 antibody, Eya1 antibody, eya1.L antibody

Background: EYA1 is a member of the eyes absent (EYA) family of proteins. EYA1 may play a role in the developing kidney, branchial arches, eye, and ear. Mutations of this gene have been associated with branchiootorenal dysplasia syndrome, branchiootic syndrome, and sporadic cases of congenital cataracts and ocular anterior segment anomalies. A similar protein in mice can act as a transcriptional activator.This gene encodes a member of the eyes absent (EYA) family of proteins. The encoded protein may play a role in the developing kidney, branchial arches, eye, and ear. Mutations of this gene have been associated with branchiootorenal dysplasia syndrome, branchiootic syndrome, and sporadic cases of congenital cataracts and ocular anterior segment anomalies. A similar protein in mice can act as a transcriptional activator. Four transcript variants encoding three distinct isoforms have been identified for this gene.

Molecular Weight: 61 kDa

Gene ID: 2138

NCBI Accession: NP_742057

UniProt: Q99502

Pathways: Sensory Perception of Sound, Positive Regulation of Response to DNA Damage Stimulus