Tiparp antibody

Catalog No. ABIN2458046

Product Details anti-Tiparp Antibody

Target: Tiparp (TCDD-Inducible Poly(ADP-Ribose) Polymerase (Tiparp))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Tiparp antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TIPARP.

Application Details

Application Notes: TIPARP antibody can be used for detection of TIPARP by ELISA at 1:312500. TIPARP antibody can be used for detection of TIPARP by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store TIPARP antibody at -20 °C.

Target Details for Tiparp

Target: Tiparp (TCDD-Inducible Poly(ADP-Ribose) Polymerase (Tiparp))

Alternative Name: TIPARP (Tiparp Products)

Synonyms: TIPARP antibody, fc03g05 antibody, sb:cb841 antibody, si:dkey-33k14.4 antibody, wu:fc03g05 antibody, zgc:153056 antibody, ddf1 antibody, parp7 antibody, parp-1 antibody, parp-7 antibody, ARTD14 antibody, PARP7 antibody, pART14 antibody, AW558171 antibody, RM1 antibody, TCDD inducible poly(ADP-ribose) polymerase antibody, TCDD-inducible poly(ADP-ribose) polymerase antibody, TCDD-inducible poly [ADP-ribose] polymerase antibody, TIPARP antibody, tiparp antibody, LOC100018933 antibody, Tiparp antibody

Background: TIPARP is a poly [ADP-ribose] polymerase using NAD+ as a substrate to transfer ADP-ribose onto glutamic acid residues of a protein acceptor, repeated rounds of ADP-ribosylation leads to the formation of poly (ADPribose) chains on the protein, thereby altering the function of the target protein. TIPARP may play a role in the adaptative response to chemical exposure (TCDD) and thereby mediates certain effects of the chemicals.

Molecular Weight: 76 kDa

Gene ID: 25976

NCBI Accession: NP_056323

UniProt: Q7Z3E1

Pathways: Platelet-derived growth Factor Receptor Signaling