ONECUT2 antibody

Catalog No. ABIN2458269

Product Details anti-ONECUT2 Antibody

Target: ONECUT2 (One Cut Homeobox 2 (ONECUT2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ONECUT2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human ONECUT2.

Application Details

Application Notes: ONECUT2 antibody can be used for detection of ONECUT2 by ELISA at 1:1562500. ONECUT2 antibody can be used for detection of ONECUT2 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store ONECUT2 antibody at -20 °C.

Target Details for ONECUT2

Target: ONECUT2 (One Cut Homeobox 2 (ONECUT2))

Alternative Name: ONECUT2 (ONECUT2 Products)

Synonyms: C730009D12 antibody, OC-2 antibody, Oc2 antibody, OC2 antibody, RGD1564677 antibody, one cut domain, family member 2 antibody, one cut homeobox 2 antibody, Onecut2 antibody, ONECUT2 antibody

Background: ONECUT2 is a member of the transcription factors of the ONECUT class, whose prototype is hepatocyte nuclear factor (HNF)-6. The distribution of OC-2 mRNA in humans is tissue-restricted, the strongest expression being detected in the liver and skin. ONECUT2 participates in the network of transcription factors required for liver differentiation and metabolism. This gene encodes a member of the onecut family of transcription factors, which are characterized by a cut domain and an atypical homeodomain. The protein binds to specific DNA sequences and stimulates expression of target genes, including genes involved in melanocyte and hepatocyte differentiation.

Molecular Weight: 54 kDa

Gene ID: 9480

NCBI Accession: NP_004843

UniProt: O95948