AGFG1 antibody

Catalog No. ABIN2458509

Product Details anti-AGFG1 Antibody

Target: AGFG1 (HRB) (HIV-1 Rev Binding Protein (HRB))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AGFG1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human HRB.

Application Details

Application Notes: HRB antibody can be used for detection of HRB by ELISA at 1:62500. HRB antibody can be used for detection of HRB by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store HRB antibody at -20 °C.

Target Details for AGFG1

Target: AGFG1 (HRB) (HIV-1 Rev Binding Protein (HRB))

Alternative Name: HRB (HRB Products)

Synonyms: HRB antibody, RAB antibody, RIP antibody, AU045498 antibody, C130049H11Rik antibody, C85612 antibody, D730048C23Rik antibody, Hrb antibody, Rip antibody, hrb antibody, agfg1 antibody, wu:fb14f05 antibody, wu:fi19d11 antibody, MGC83726 antibody, MGC97591 antibody, ArfGAP with FG repeats 1 antibody, ArfGAP with FG repeats 1a antibody, ArfGAP with FG repeats 1 S homeolog antibody, KRR1 small subunit processome component homolog antibody, AGFG1 antibody, Agfg1 antibody, agfg1a antibody, agfg1.S antibody, agfg1 antibody, LOC5565923 antibody

Background: HRB is related to nucleoporins, a class of proteins that mediate nucleocytoplasmic transport. HRB binds the activation domain of the human immunodeficiency virus Rev protein when Rev is assembled onto its RNA target, and is required for the nuclear export of Rev-directed RNAs.The protein encoded by this gene is related to nucleoporins, a class of proteins that mediate nucleocytoplasmic transport. This encoded protein binds the Rev activation domain when Rev is assembled onto its RNA target and can significantly enhance Rev activity when overexpressed. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Molecular Weight: 58 kDa

Gene ID: 3267

NCBI Accession: NP_004495

UniProt: P52594