MARCH5 antibody

Catalog No. ABIN2458720

Product Details anti-MARCH5 Antibody

Target: MARCH5 (Membrane-Associated Ring Finger (C3HC4) 5 (MARCH5))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MARCH5 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human MARCH5.

Application Details

Application Notes: MARCH5 antibody can be used for detection of 40242 by ELISA at 1:1562500. MARCH5 antibody can be used for detection of 40242 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store MARCH5 antibody at -20 °C.

Target Details for MARCH5

Target: MARCH5 (Membrane-Associated Ring Finger (C3HC4) 5 (MARCH5))

Alternative Name: MARCH5 (MARCH5 Products)

Synonyms: march5 antibody, MARCH5 antibody, mitol antibody, rnf153 antibody, march-v antibody, zgc:162966 antibody, MARCH-V antibody, Mar-05 antibody, MITOL antibody, RNF153 antibody, 1810015H18Rik antibody, 2310008I22Rik antibody, 2700055A20Rik antibody, 5730499H23Rik antibody, E130202O05Rik antibody, Marchv antibody, Rnf153 antibody, membrane-associated ring finger (C3HC4) 5 antibody, membrane associated ring-CH-type finger 5 antibody, membrane associated ring-CH-type finger 5 L homeolog antibody, march5 antibody, MARCH5 antibody, march5.L antibody, March5 antibody

Background: MARCH5 is an ubiquitin ligase of the mitochondrial outer membrane that plays a role in the control of mitochondrial morphology by regulating mitofusin-2 (MFN2) and DRP1 (DNM1L).MARCH5 is a ubiquitin ligase of the mitochondrial outer membrane that plays a role in the control of mitochondrial morphology by regulating mitofusin-2 (MFN2, MIM 608507) and DRP1 (DNM1L, MIM 603850) (Nakamura et al., 2006 [PubMed 16936636]).

Molecular Weight: 31 kDa

Gene ID: 54708

NCBI Accession: NP_060294

UniProt: Q9NX47