GGCX antibody
-
- Target See all GGCX Antibodies
- GGCX (gamma-Glutamyl Carboxylase (GGCX))
-
Reactivity
- Human, Mouse, Rat
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- This GGCX antibody is un-conjugated
-
Application
- ELISA, Western Blotting (WB)
- Purification
- Antibody is purified by peptide affinity chromatography method.
- Immunogen
- Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human GGCX.
- Top Product
- Discover our top product GGCX Primary Antibody
-
-
- Application Notes
- GGCX antibody can be used for detection of GGCX by ELISA at 1:1562500. GGCX antibody can be used for detection of GGCX by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Reconstitution
- Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.
- Concentration
- 1 mg/mL
- Buffer
- Antibody is lyophilized in PBS buffer with 2 % sucrose.
- Handling Advice
- As with any antibody avoid repeat freeze-thaw cycles.
- Storage
- 4 °C/-20 °C
- Storage Comment
- For short periods of storage (days) store at 4 °C. For longer periods of storage, store GGCX antibody at -20 °C.
-
- Target
- GGCX (gamma-Glutamyl Carboxylase (GGCX))
- Alternative Name
- GGCX (GGCX Products)
- Synonyms
- GGCX antibody, cb751 antibody, si:ch1073-230p18.3 antibody, zgc:158736 antibody, ggcx antibody, GGC antibody, vkcfd1 antibody, CG13927 antibody, DgammaC antibody, Dmel\\CG13927 antibody, dGC antibody, dgammaC antibody, gammaC antibody, VKCFD1 antibody, gamma-glutamyl carboxylase antibody, gamma-glutamyl carboxylase L homeolog antibody, GGCX antibody, ggcx antibody, GC antibody, sce5891 antibody, ggcx.L antibody, Ggcx antibody
- Background
- GGCX is an enzyme which catalyzes the posttranslational modification of vitamin K-dependent protein. Many of these vitamin K-dependent proteins are involved in coagulation so the function of the encoded enzyme is essential for hemostasis. Mutations in this gene are associated with vitamin K-dependent coagulation defect and PXE-like disorder with multiple coagulation factor deficiency.Gamma-glutamyl carboxylase accomplishes the posttranslational modification required for the activity of all of the vitamin K-dependent proteins (Wu et al., 1991 [PubMed 1749935]). These include some of the blood coagulation and anticoagulation proteins as well as bone gamma-carboxyglutamic acid (Gla) protein (BGLAP, MIM 112260) and bone matrix protein (MGP, MIM 154870).
- Molecular Weight
- 87 kDa
- Gene ID
- 2677
- NCBI Accession
- NP_000812
- UniProt
- P38435
- Pathways
- SARS-CoV-2 Protein Interactome
-