DEGS1 antibody

Catalog No. ABIN2458939

Product Details anti-DEGS1 Antibody

Target: DEGS1 (Sphingolipid Delta(4)-Desaturase DES1 (DEGS1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DEGS1 antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human DEGS1.

Application Details

Application Notes: DEGS1 antibody can be used for detection of DEGS1 by ELISA at 1:312500. DEGS1 antibody can be used for detection of DEGS1 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store DEGS1 antibody at -20 °C.

Target Details for DEGS1

Target: DEGS1 (Sphingolipid Delta(4)-Desaturase DES1 (DEGS1))

Alternative Name: DEGS1 (DEGS1 Products)

Synonyms: DEGS antibody, DEGS-1 antibody, DES1 antibody, Des-1 antibody, FADS7 antibody, MLD antibody, degs antibody, im:6909319 antibody, wu:fa25h01 antibody, wu:fb81d06 antibody, Degs antibody, AA536663 antibody, Des1 antibody, Mdes antibody, delta 4-desaturase, sphingolipid 1 antibody, delta(4)-desaturase, sphingolipid 1 antibody, DEGS1 antibody, degs1 antibody, Degs1 antibody

Background: DEGS1 is a member of the membrane fatty acid desaturase family which is responsible for inserting double bonds into specific positions in fatty acids. This protein contains three His-containing consensus motifs that are characteristic of a group of membrane fatty acid desaturases. It is predicted to be a multiple membrane-spanning protein localized to the endoplasmic reticulum. Overexpression of this protein inhibited biosynthesis of the EGF receptor, suggesting a possible role of a fatty acid desaturase in regulating biosynthetic processing of the EGF receptor.This gene encodes a member of the membrane fatty acid desaturase family which is responsible for inserting double bonds into specific positions in fatty acids. This protein contains three His-containing consensus motifs that are characteristic of a group of membrane fatty acid desaturases. It is predicted to be a multiple membrane-spanning protein localized to the endoplasmic reticulum. Overexpression of this gene inhibited biosynthesis of the EGF receptor, suggesting a possible role of a fatty acid desaturase in regulating biosynthetic processing of the EGF receptor. Two splice variants have been identified.

Molecular Weight: 38 kDa

Gene ID: 8560

NCBI Accession: NP_003667

UniProt: O15121