CRYZ antibody

Catalog No. ABIN2458983

Product Details anti-CRYZ Antibody

Target: CRYZ (Crystallin, zeta (CRYZ))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CRYZ antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CRYZ.

Application Details

Application Notes: CRYZ antibody can be used for detection of CRYZ by ELISA at 1:1562500. CRYZ antibody can be used for detection of CRYZ by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store CRYZ antibody at -20 °C.

Target Details for CRYZ

Target: CRYZ (Crystallin, zeta (CRYZ))

Alternative Name: CRYZ (CRYZ Products)

Synonyms: CRYZ antibody, wu:fq09a05 antibody, zgc:110776 antibody, cryz antibody, MGC79715 antibody, Sez9 antibody, crystallin zeta antibody, crystallin, zeta (quinone reductase) antibody, crystallin zeta L homeolog antibody, zeta-crystallin antibody, crystallin, zeta antibody, CRYZ antibody, cryz antibody, cryz.L antibody, PTRG_02583 antibody, PTRG_07455 antibody, VDBG_03981 antibody, Cryz antibody

Background: Crystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. The former class is also called phylogenetically-restricted crystallins. CRYZ is a taxon-specific crystallin protein which has NADPH-dependent quinone reductase activity distinct from other known quinone reductases. It lacks alcohol dehydrogenase activity although by similarity it is considered a member of the zinc-containing alcohol dehydrogenase family. Unlike other mammalian species, in humans, lens expression is low.Crystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. The former class is also called phylogenetically-restricted crystallins. This gene encodes a taxon-specific crystallin protein which has NADPH-dependent quinone reductase activity distinct from other known quinone reductases. It lacks alcohol dehydrogenase activity although by similarity it is considered a member of the zinc-containing alcohol dehydrogenase family. Unlike other mammalian species, in humans, lens expression is low. One pseudogene is known to exist.

Molecular Weight: 35 kDa

Gene ID: 1429

NCBI Accession: NP_001880

UniProt: Q08257