CHST15 antibody

Catalog No. ABIN2459075

Product Details anti-CHST15 Antibody

Target: CHST15 (Carbohydrate (N-Acetylgalactosamine 4-Sulfate 6-O) Sulfotransferase 15 (CHST15))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CHST15 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human GALNAC4S-6ST.

Application Details

Application Notes: GALNAC4S-6ST antibody can be used for detection of GALNAC4S-6ST by ELISA at 1:12500. GALNAC4S-6ST antibody can be used for detection of GALNAC4S-6ST by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store GALNAC4S-6ST antibody at -20 °C.

Target Details for CHST15

Target: CHST15 (Carbohydrate (N-Acetylgalactosamine 4-Sulfate 6-O) Sulfotransferase 15 (CHST15))

Alternative Name: GALNAC4S-6ST (CHST15 Products)

Synonyms: GALNAC4S-6ST antibody, BRAG antibody, RP11-47G11.1 antibody, 4631426J05Rik antibody, GalNAcS-6ST antibody, MAd5 antibody, mKIAA0598 antibody, GalNAc4S6ST antibody, Galnac4s-6st antibody, carbohydrate sulfotransferase 15 antibody, carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 antibody, CHST15 antibody, chst15 antibody, Chst15 antibody

Background: GALNAC4S-6ST is a sulfotransferase that transfers sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to the C-6 hydroxyl group of the GalNAc 4-sulfate residue of chondroitin sulfate A and forms chondroitin sulfate E containing GlcA-GalNAc (4,6-SO (4)) repeating units. It also transfers sulfate to a unique non-reducing terminal sequence, GalNAc (4SO4)-GlcA (2SO4)-GalNAc (6SO4), to yield a highly sulfated structure similar to the structure found in thrombomodulin chondroitin sulfate. GALNAC4S-6ST may also act as a B-cell receptor involved in BCR ligation-mediated early activation that mediate regulatory signals key to B-cell development and/or regulation of B-cell-specific RAG expression, however such results are unclear in vivo.

Molecular Weight: 65 kDa

Gene ID: 51363

NCBI Accession: NP_056976

UniProt: Q7LFX5

Pathways: Glycosaminoglycan Metabolic Process