SLITRK1 antibody

Catalog No. ABIN2459375

Product Details anti-SLITRK1 Antibody

Target: SLITRK1 (SLIT and NTRK-Like Family, Member 1 (SLITRK1))

Reactivity: Rat, Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLITRK1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SLITRK1.

Application Details

Application Notes: SLITRK1 antibody can be used for detection of SLITRK1 by ELISA at 1:312500. SLITRK1 antibody can be used for detection of SLITRK1 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store SLITRK1 antibody at -20 °C.

Target Details for SLITRK1

Target: SLITRK1 (SLIT and NTRK-Like Family, Member 1 (SLITRK1))

Alternative Name: SLITRK1 (SLITRK1 Products)

Synonyms: DKFZp459G0529 antibody, LRRC12 antibody, TTM antibody, 3200001I04Rik antibody, SLIT and NTRK like family member 1 antibody, SLIT and NTRK-like family, member 1 antibody, SLITRK1 antibody, slitrk1 antibody, Slitrk1 antibody

Background: Members of the SLITRK family, such as SLITRK1, are integral membrane proteins with 2 N-terminal leucine-rich repeat (LRR) domains similar to those of SLIT proteins. Most SLITRKs, but not SLITRK1, also have C-terminal regions that share homology with neurotrophin receptors. SLITRKs are expressed predominantly in neural tissues and have neurite-modulating activity.Members of the SLITRK family, such as SLITRK1, are integral membrane proteins with 2 N-terminal leucine-rich repeat (LRR) domains similar to those of SLIT proteins (see SLIT1, MIM 603742). Most SLITRKs, but not SLITRK1, also have C-terminal regions that share homology with neurotrophin receptors (see NTRK1, MIM 191315). SLITRKs are expressed predominantly in neural tissues and have neurite-modulating activity (Aruga et al., 2003 [PubMed 14557068]).

Molecular Weight: 78 kDa

Gene ID: 114798

NCBI Accession: NP_443142

UniProt: Q96PX8