RDH12 antibody

Catalog No. ABIN2459608

Product Details anti-RDH12 Antibody

Target: RDH12 (Retinol Dehydrogenase 12 (All-Trans/9-Cis/11-Cis) (RDH12))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RDH12 antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human RDH12.

Application Details

Application Notes: RDH12 antibody can be used for detection of RDH12 by ELISA at 1:312500. RDH12 antibody can be used for detection of RDH12 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store RDH12 antibody at -20 °C.

Target Details for RDH12

Target: RDH12 (Retinol Dehydrogenase 12 (All-Trans/9-Cis/11-Cis) (RDH12))

Alternative Name: RDH12 (RDH12 Products)

Synonyms: wu:fj43a10 antibody, zgc:92430 antibody, A930033N07Rik antibody, LCA13 antibody, LCA3 antibody, RP53 antibody, SDR7C2 antibody, DSSDR2 antibody, retinol dehydrogenase 12 (all-trans/9-cis/11-cis) antibody, retinol dehydrogenase 12 antibody, Retinol dehydrogenase 12 antibody, RDH12 antibody, rdh12 antibody, MAV_1968 antibody, CC1G_02720 antibody, Bm1_36660 antibody, PTRG_03574 antibody, PTRG_05326 antibody, PTRG_08067 antibody, LOC100282710 antibody, LOC100285880 antibody, LOC100226769 antibody, Rdh12 antibody

Background: RDH12 is an NADPH-dependent retinal reductase whose highest activity is toward 9-cis and all-trans-retinol. RDH12 also plays a role in the metabolism of short-chain aldehydes but does not exhibit steroid dehydrogenase activity. Defects in this gene are a cause of Leber congenital amaurosis type 3 (LCA3).The protein encoded by this gene is an NADPH-dependent retinal reductase whose highest activity is toward 9-cis and all-trans-retinol. The encoded enzyme also plays a role in the metabolism of short-chain aldehydes but does not exhibit steroid dehydrogenase activity. Defects in this gene are a cause of Leber congenital amaurosis type 3 (LCA3).

Molecular Weight: 35 kDa

Gene ID: 145226

NCBI Accession: NP_689656

UniProt: Q96NR8