MPP7 antibody

Catalog No. ABIN2459648

Product Details anti-MPP7 Antibody

Target: MPP7 (Membrane Protein, Palmitoylated 7 (MAGUK p55 Subfamily Member 7) (MPP7))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MPP7 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human MPP7.

Application Details

Application Notes: MPP7 antibody can be used for detection of MPP7 by ELISA at 1:62500. MPP7 antibody can be used for detection of MPP7 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store MPP7 antibody at -20 °C.

Target Details for MPP7

Target: MPP7 (Membrane Protein, Palmitoylated 7 (MAGUK p55 Subfamily Member 7) (MPP7))

Alternative Name: MPP7 (MPP7 Products)

Synonyms: 1110068J02Rik antibody, 2810038M04Rik antibody, 5430426E14Rik antibody, AI415104 antibody, Gm955 antibody, dlg3 antibody, hmp antibody, membrane palmitoylated protein 7 antibody, membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7) antibody, membrane protein, palmitoylated 7a (MAGUK p55 subfamily member 7) antibody, MPP7 antibody, Mpp7 antibody, mpp7a antibody

Background: MPP7 acts as an important adapter that promotes epithelial cell polarity and tight junction formation via its interaction with DLG1. MPP7 is involved in the assembly of protein complexes at sites of cell-cell contact.Membrane-associated guanylate kinases (MAGUKs) are important adaptor proteins involved in the assembly of protein complexes at sites of cell-cell contact. They are found in synapses, adherens junctions, and tight junctions. All MAGUKs contain at least 1 PDZ domain, an SH3 domain, and a GUK domain, and many contain 1 or 2 L27 domains, which are involved in multimerization of MAGUKs. MPP7 belongs to the p55 stardust subfamily of MAGUKs, which is named for a Drosophila gene required for establishment of cell polarity in the developing fly embryo (Bohl et al., 2007 [PubMed 17237226]).

Molecular Weight: 65 kDa

Gene ID: 143098

NCBI Accession: NP_775767

UniProt: Q5T2T1

Pathways: Cell-Cell Junction Organization