ADAMTS18 antibody

Catalog No. ABIN2459683

Product Details anti-ADAMTS18 Antibody

Target: ADAMTS18 (ADAM Metallopeptidase with thrombospondin Type 1 Motif, 18 (ADAMTS18))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ADAMTS18 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human ADAMTS18.

Application Details

Application Notes: ADAMTS18 antibody can be used for detection of ADAMTS18 by ELISA at 1:12500. ADAMTS18 antibody can be used for detection of ADAMTS18 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store ADAMTS18 antibody at -20 °C.

Target Details for ADAMTS18

Target: ADAMTS18 (ADAM Metallopeptidase with thrombospondin Type 1 Motif, 18 (ADAMTS18))

Alternative Name: ADAMTS18 (ADAMTS18 Products)

Synonyms: 9630038L21 antibody, ADAMTS21 antibody, E130314N14Rik antibody, KNO2 antibody, RGD1560118 antibody, a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 18 antibody, ADAM metallopeptidase with thrombospondin type 1 motif 18 antibody, ADAM metallopeptidase with thrombospondin type 1 motif, 18 antibody, Adamts18 antibody, ADAMTS18 antibody

Background: ADAMTS18 is a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. ADAMTS family members share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The protein has a high sequence similarity to the protein encoded by gene ADAMTS16, another family member. It is thought to function as a tumor suppressor. Alternatively spliced transcript variants have been identified, but their biological validity has not been determined. This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. ADAMTS family members share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The protein encoded by this gene has a high sequence similarity to the protein encoded by gene ADAMTS16, another family member. It is thought to function as a tumor suppressor. Alternatively spliced transcript variants have been identified, but their biological validity has not been determined.

Molecular Weight: 104 kDa

Gene ID: 170692

NCBI Accession: NP_955387

UniProt: Q8TE60