IDI1 antibody

Catalog No. ABIN2459801

Product Details anti-IDI1 Antibody

Target: IDI1 (Isopentenyl-Diphosphate delta Isomerase 1 (IDI1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IDI1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human IDI1.

Application Details

Application Notes: IDI1 antibody can be used for detection of IDI1 by ELISA at 1:1562500. IDI1 antibody can be used for detection of IDI1 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store IDI1 antibody at -20 °C.

Target Details for IDI1

Target: IDI1 (Isopentenyl-Diphosphate delta Isomerase 1 (IDI1))

Alternative Name: IDI1 (IDI1 Products)

Synonyms: zgc:114138 antibody, 4832416K17Rik antibody, ipp1 antibody, ippl1 antibody, IPP1 antibody, IPPI1 antibody, isopentenyl-diphosphate delta isomerase 1 antibody, isopentenyl-diphosphate delta isomerase antibody, isopentenyl-diphosphate delta isomerase 1 L homeolog antibody, idi1 antibody, Idi1 antibody, idi1.L antibody, IDI1 antibody

Background: IDI1 is a peroxisomally-localized enzyme that catalyzes the interconversion of isopentenyl diphosphate (IPP) to its highly electrophilic isomer, dimethylallyl diphosphate (DMAPP), which are the substrates for the successive reaction that results in the synthesis of farnesyl diphosphate and, ultimately, cholesterol. It has been shown in peroxisomal deficiency diseases such as Zellweger syndrome and neonatal adrenoleukodystrophy that there is reduction in IPP isomerase activity.IDI1 encodes a peroxisomally-localized enzyme that catalyzes the interconversion of isopentenyl diphosphate (IPP) to its highly electrophilic isomer, dimethylallyl diphosphate (DMAPP), which are the substrates for the successive reaction that results in the synthesis of farnesyl diphosphate and, ultimately, cholesterol. It has been shown in peroxisomal deficiency diseases such as Zellweger syndrome and neonatal adrenoleukodystrophy that there is reduction in IPP isomerase activity.

Molecular Weight: 32 kDa

Gene ID: 3422

NCBI Accession: NP_004499

UniProt: Q13907