HTRA4 antibody

Catalog No. ABIN2459938

Product Details anti-HTRA4 Antibody

Target: HTRA4 (HtrA Serine Peptidase 4 (HTRA4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HTRA4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human HTRA4.

Application Details

Application Notes: HTRA4 antibody can be used for detection of HTRA4 by ELISA at 1:312500. HTRA4 antibody can be used for detection of HTRA4 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store HTRA4 antibody at -20 °C.

Target Details for HTRA4

Target: HTRA4 (HtrA Serine Peptidase 4 (HTRA4))

Alternative Name: HTRA4 (HTRA4 Products)

Synonyms: B430206E18Rik antibody, RGD1306242 antibody, HtrA serine peptidase 4 antibody, HTRA4 antibody, Htra4 antibody

Background: HTRA4 is a member of the HtrA family of proteases. The protein contains a putative signal peptide, an insulin growth factor binding domain, a Kazal protease inhibitor domain, a conserved trypsin domain and a PDZ domain. Based on studies on other related family members, this enzyme may function as a secreted oligomeric chaperone protease to degrade misfolded secretory proteins. Other human HtrA proteins have been implicated in arthritis, tumor suppression, unfolded stress response, apoptosis, and aging.

Molecular Weight: 51 kDa

Gene ID: 203100

NCBI Accession: NP_710159

UniProt: P83105