AEBP1 antibody

Catalog No. ABIN2460251

Product Details anti-AEBP1 Antibody

Target: AEBP1 (AE Binding Protein 1 (AEBP1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AEBP1 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human AEBP1.

Application Details

Application Notes: AEBP1 antibody can be used for detection of AEBP1 by ELISA at 1:1562500. AEBP1 antibody can be used for detection of AEBP1 by western blot at 0.2-5.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store AEBP1 antibody at -20 °C.

Target Details for AEBP1

Target: AEBP1 (AE Binding Protein 1 (AEBP1))

Alternative Name: AEBP1 (AEBP1 Products)

Synonyms: ACLP antibody, AE binding protein 1 antibody, Closa_4071 antibody, AEBP1 antibody, Aebp1 antibody

Background: The adipocyte enhancer binding protein 1 (AEBP1) is a transcriptional repressor with carboxypeptidase (CP) activity. This protein binds to a regulatory sequence, adipocyte enhancer 1 (AE-1), located in the proximal promoter region of the adipose P2 (aP2) gene, which encodes the adipocyte fatty-acid binding protein. It is characterized as a member of the regulatory B-like CP family. This protein seems to be activated by a novel mechanism, whereby the direct binding of DNA enhances its protease activity. AEBP1 may play a role in differentiated vascular smooth muscle cells.

Molecular Weight: 131 kDa

Gene ID: 165

NCBI Accession: NP_001120

UniProt: Q14113