T-Box 19 antibody
-
- Target See all T-Box 19 (TBX19) Antibodies
- T-Box 19 (TBX19)
-
Reactivity
- Human
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- This T-Box 19 antibody is un-conjugated
-
Application
- Western Blotting (WB), ELISA
- Purification
- Antibody is purified by peptide affinity chromatography method.
- Immunogen
- Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TBX19.
- Top Product
- Discover our top product TBX19 Primary Antibody
-
-
- Application Notes
- TBX19 antibody can be used for detection of TBX19 by ELISA at 1:312500. TBX19 antibody can be used for detection of TBX19 by western blot at 0.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Reconstitution
- Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.
- Concentration
- 1 mg/mL
- Buffer
- Antibody is lyophilized in PBS buffer with 2 % sucrose.
- Handling Advice
- As with any antibody avoid repeat freeze-thaw cycles.
- Storage
- 4 °C/-20 °C
- Storage Comment
- For short periods of storage (days) store at 4 °C. For longer periods of storage, store TBX19 antibody at -20 °C.
-
- Target
- T-Box 19 (TBX19)
- Alternative Name
- TBX19 (TBX19 Products)
- Synonyms
- TBX19 antibody, TBS19 antibody, TPIT antibody, dJ747L4.1 antibody, CH-TBXT antibody, TBXT antibody, AU019250 antibody, D1Ertd754e antibody, Tpit antibody, T-box 19 antibody, TBX19 antibody, Tbx19 antibody
- Background
- TBX19 is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene is the human ortholog of mouse Tbx19/Tpit gene. Studies in mouse show that Tpit protein is present only in the two pituitary pro-opiomelanocortin (POMC)-expressing lineages, the corticotrophs and melanotrophs. Mutations in the human ortholog were found in patients with isolated deficiency of pituitary POMC-derived ACTH, suggesting an essential role for this gene in differentiation of the pituitary POMC lineage.This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. Mutations in this gene were found in patients with isolated deficiency of pituitary POMC-derived ACTH, suggesting an essential role for this gene in differentiation of the pituitary POMC lineage. ACTH deficiency is characterized by adrenal insufficiency symptoms such as weight loss, lack of appetite (anorexia), weakness, nausea, vomiting, and low blood pressure. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
- Molecular Weight
- 48 kDa
- Gene ID
- 9095
- NCBI Accession
- NP_005140
- UniProt
- O60806
-