MXD4 antibody

Catalog No. ABIN2460569

Product Details anti-MXD4 Antibody

Target: MXD4 (MAX Dimerization Protein 4 (MXD4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MXD4 antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human MXD4.

Application Details

Application Notes: MXD4 antibody can be used for detection of MXD4 by ELISA at 1:12500. MXD4 antibody can be used for detection of MXD4 by western blot at 0.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store MXD4 antibody at -20 °C.

Target Details for MXD4

Target: MXD4 (MAX Dimerization Protein 4 (MXD4))

Alternative Name: MXD4 (MXD4 Products)

Synonyms: MAD4 antibody, MST149 antibody, MSTP149 antibody, bHLHc12 antibody, xmad4 antibody, mst149 antibody, bhlhc12 antibody, mstp149 antibody, MGC84841 antibody, MXD4 antibody, 2810410A03Rik antibody, Mad4 antibody, MAX dimerization protein 4 antibody, Max dimerization protein 4 antibody, MAX dimerization protein 4 S homeolog antibody, microRNA 4800 antibody, MXD4 antibody, Mxd4 antibody, mxd4.S antibody, MIR4800 antibody, mxd4 antibody

Background: MXD4 is a member of the MAD gene family . The MAD genes encode basic helix-loop-helix-leucine zipper proteins that heterodimerize with MAX protein, forming a transcriptional repression complex. The MAD proteins compete for MAX binding with MYC, which heterodimerizes with MAX forming a transcriptional activation complex. Studies in rodents suggest that the MAD genes are tumor suppressors and contribute to the regulation of cell growth in differentiating tissues.

Molecular Weight: 24 kDa

Gene ID: 10608

NCBI Accession: NP_006445

UniProt: Q14582