MRGBP antibody

Catalog No. ABIN2460698

Product Details anti-MRGBP Antibody

Target: MRGBP (MRG-Binding Protein (MRGBP))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MRGBP antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human C20orf20.

Application Details

Application Notes: C20orf20 antibody can be used for detection of C20orf20 by ELISA at 1:312500. C20orf20 antibody can be used for detection of C20orf20 by western blot at 0.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store C20orf20 antibody at -20 °C.

Target Details for MRGBP

Target: MRGBP (MRG-Binding Protein (MRGBP))

Alternative Name: C20orf20 (MRGBP Products)

Synonyms: C20orf20 antibody, Eaf7 antibody, MRG15BP antibody, URCC4 antibody, c20orf20 antibody, zgc:73167 antibody, 1600027N09Rik antibody, AW060503 antibody, C80444 antibody, MRG domain binding protein antibody, MRG/MORF4L-binding protein antibody, MRG-binding protein antibody, putative mrg-binding protein antibody, MRG/MORF4L binding protein antibody, MRGBP antibody, LOC5577096 antibody, CpipJ_CPIJ006487 antibody, CpipJ_CPIJ017611 antibody, Smp_130630 antibody, mrgbp antibody, Mrgbp antibody

Background: C20orf20 belongs to the EAF7 family. It is a component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. NuA4 may also play a direct role in DNA repair when recruited to sites of DNA damage.

Molecular Weight: 22 kDa

Gene ID: 55257

NCBI Accession: NP_060740

UniProt: Q9NV56