PREB antibody

Catalog No. ABIN2460871

Product Details anti-PREB Antibody

Target: PREB (Prolactin Regulatory Element Binding (PREB))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PREB antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human PREB.

Application Details

Application Notes: PREB antibody can be used for detection of PREB by ELISA at 1:312500. PREB antibody can be used for detection of PREB by western blot at 0.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store PREB antibody at -20 °C.

Target Details for PREB

Target: PREB (Prolactin Regulatory Element Binding (PREB))

Alternative Name: PREB (PREB Products)

Synonyms: C85705 antibody, SEC12 antibody, prolactin regulatory element binding antibody, PREB antibody, Preb antibody

Background: PREB encodes a protein that specifically binds to a Pit1-binding element of the prolactin (PRL) promoter. This protein may act as a transcriptional regulator and is thought to be involved in some of the developmental abnormalities observed in patients with partial trisomy 2p.

Molecular Weight: 45 kDa

Gene ID: 10113

NCBI Accession: NP_037520

UniProt: Q9HCU5

Pathways: ER-Nucleus Signaling