CPSF1 antibody

Catalog No. ABIN2462246

Product Details anti-CPSF1 Antibody

Target: CPSF1 (Cleavage and Polyadenylation Specific Factor 1, 160kDa (CPSF1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CPSF1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CPSF1.

Application Details

Application Notes: CPSF1 antibody can be used for detection of CPSF1 by ELISA at 1:62500. CPSF1 antibody can be used for detection of CPSF1 by western blot at 0.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store CPSF1 antibody at -20 °C.

Target Details for CPSF1

Target: CPSF1 (Cleavage and Polyadenylation Specific Factor 1, 160kDa (CPSF1))

Alternative Name: CPSF1 (CPSF1 Products)

Synonyms: CG10110 antibody, CPSF antibody, CPSF-160 antibody, CPSF160 antibody, Cpsf antibody, Dmel\\CG10110 antibody, anon-WO0118547.217 antibody, cpsf antibody, dCPSF-160 antibody, wu:fb24c01 antibody, CPSF1 antibody, DKFZp469K0832 antibody, HSU37012 antibody, P/cl.18 antibody, ATCPSF160 antibody, K17N15.21 antibody, K17N15_21 antibody, cleavage and polyadenylation specificity factor 160 antibody, cleavage and polyadenylation specific factor 1 antibody, Cleavage and polyadenylation specificity factor 160 antibody, cleavage and polyadenylation specific factor 1 L homeolog antibody, cleavage and polyadenylation specificity factor subunit 1 antibody, cleavage and polyadenylation specificity factor 160 antibody, Cpsf1 antibody, Cpsf160 antibody, cpsf1.L antibody, cpsf1 antibody, CPSF1 antibody, Tsp_05366 antibody, CPSF160 antibody

Background: CPSF1 is a component of the cleavage and polyadenylation specificity factor (CPSF) complex that plays a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly (A) polymerase and other factors to bring about cleavage and poly (A) addition. This subunit is involved in the RNA recognition step of the polyadenylation reaction.

Molecular Weight: 161 kDa

Gene ID: 29894

NCBI Accession: NP_037423

UniProt: Q10570