SRSF10 antibody

Catalog No. ABIN2462322

Product Details anti-SRSF10 Antibody

Target: SRSF10 (serine/arginine-Rich Splicing Factor 10 (SRSF10))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SRSF10 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human FUSIP1.

Application Details

Application Notes: FUSIP1 antibody can be used for detection of FUSIP1 by ELISA at 1:62500. FUSIP1 antibody can be used for detection of FUSIP1 by western blot at 0.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store FUSIP1 antibody at -20 °C.

Target Details for SRSF10

Target: SRSF10 (serine/arginine-Rich Splicing Factor 10 (SRSF10))

Alternative Name: FUSIP1 (SRSF10 Products)

Synonyms: FUSIP1 antibody, SFRS13A antibody, FUSIP2 antibody, NSSR antibody, SFRS13 antibody, SRp38 antibody, SRrp40 antibody, TASR antibody, TASR1 antibody, TASR2 antibody, Fusip1 antibody, NSSR1 antibody, NSSR2 antibody, Nssr antibody, Sfrs13a antibody, Srsf13a antibody, fusip1 antibody, fusip2 antibody, nssr antibody, sfrs13 antibody, sfrs13a antibody, srp38 antibody, srrp40 antibody, tasr antibody, tasr1 antibody, tasr2 antibody, serine and arginine rich splicing factor 10 antibody, serine/arginine-rich splicing factor 10 antibody, serine/arginine-rich splicing factor 10 S homeolog antibody, SRSF10 antibody, Srsf10 antibody, srsf10.S antibody

Background: FUSIP1 is a member of the serine-arginine (SR) family of proteins, which is involved in constitutive and regulated RNA splicing. Members of this family are characterized by N-terminal RNP1 and RNP2 motifs, which are required for binding to RNA, and multiple C-terminal SR/RS repeats, which are important in mediating association with other cellular proteins. This protein can influence splice site selection of adenovirus E1A pre-mRNA. It interacts with the oncoprotein TLS, and abrogates the influence of TLS on E1A pre-mRNA splicing.This gene product is a member of the serine-arginine (SR) family of proteins, which is involved in constitutive and regulated RNA splicing. Members of this family are characterized by N-terminal RNP1 and RNP2 motifs, which are required for binding to RNA, and multiple C-terminal SR/RS repeats, which are important in mediating association with other cellular proteins. This protein can influence splice site selection of adenovirus E1A pre-mRNA. It interacts with the oncoprotein TLS, and abrogates the influence of TLS on E1A pre-mRNA splicing. Alternative splicing of this gene results in at least two transcript variants encoding different isoforms. In addition, transcript variants utilizing alternative polyA sites exist.This gene product is a member of the serine-arginine (SR) family of proteins, which is involved in constitutive and regulated RNA splicing. Members of this family are characterized by N-terminal RNP1 and RNP2 motifs, which are required for binding to RNA, and multiple C-terminal SR/RS repeats, which are important in mediating association with other cellular proteins. This protein can influence splice site selection of adenovirus E1A pre-mRNA. It interacts with the oncoprotein TLS, and abrogates the influence of TLS on E1A pre-mRNA splicing. Alternative splicing of this gene results in at least two transcript variants encoding different isoforms. In addition, transcript variants utilizing alternative polyA sites exist.

Molecular Weight: 31 kDa

Gene ID: 10772

NCBI Accession: NP_473357

UniProt: O75494

Pathways: Ribonucleoprotein Complex Subunit Organization