MAGEA8 antibody

Catalog No. ABIN2462552

Product Details anti-MAGEA8 Antibody

Target: MAGEA8 (Melanoma Antigen Family A, 8 (MAGEA8))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAGEA8 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human MAGEA8.

Application Details

Application Notes: MAGEA8 antibody can be used for detection of MAGEA8 by ELISA at 1:62500. MAGEA8 antibody can be used for detection of MAGEA8 by western blot at 0.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store MAGEA8 antibody at -20 °C.

Target Details for MAGEA8

Target: MAGEA8 (Melanoma Antigen Family A, 8 (MAGEA8))

Alternative Name: MAGEA8 (MAGEA8 Products)

Synonyms: Mage-a8 antibody, RGD1565778 antibody, MAGEA8 antibody, CT1.8 antibody, MAGE8 antibody, melanoma antigen, family A, 8 antibody, MAGE family member A8 antibody, Magea8 antibody, MAGEA8 antibody

Background: MAGEA8 is a member of the MAGEA family. The members of this family with 50 to 80 % sequence identity to each other. They have been implicated in some hereditary disorders, such as dyskeratosis congenita.This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80 % sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita.

Molecular Weight: 35 kDa

Gene ID: 4107

NCBI Accession: NP_005355

UniProt: Q9BUN9